100% Food Vitamin B-6, B-12, & Folate is a natural, vegetarian, Food
complex source of vitamin B-6, vitamin B-12, and folate. Various forms
of anemia often have a nutritional component [1,2] and near constant or
mid-afternoon fatigue are common symptoms. Unlike other brands, 100% Food Vitamin B-6, B-12, & Folate contains no USP vitamins or vitamin forms foreign to the human body.
Vitamin B-6:
“An understanding of the various forms and quantities of these forms in
foods is important in the evaluation of the bioavailability and
metabolism of vitamin B-6”... one of the forms that vitamin B-6 exists
is in the form of “5’0-(beta-D-glycopyransosyl) pyridoxine. To date
only plant foods have been found to contain this interesting form of
vitamin B-6” [3]. Yeast and rice bran contain more natural Food vitamin B-6 than other Foods
[4]. Vitamin B-6 was first reported in the 1930s [5]. At least one
synthetic vitamin B-6 analogue has been found to inhibit natural
vitamin B-6 action [6]. Pyridoxine HCL (hydrochloride) which is found
in most non-Food supplements, is made with
petroleum ester combined with HCL and processed with formaldehyde [7].
“Disorders treated with (B-6)...include Down’s syndrome, autism,
hyperoxaluria, gestational diabetes, carpal tunnel syndrome,
depression, and diabetic neuropathy”, but the results are consider by
some in the mainstream as having “limited value” [1]. Vitamin B-6 is
considered to be a first-line treatment for Lennox-Gastaut and some
other seizure disorders [8,9].Many problems including
anemias, premenstrual dysphoric disorder (PMDD), PMS, cardiovascular
complaints, confusion, depression, irritability, and certain immune
problems have responded to vitamin B-6 [9]. A study of healthy elderly
individuals found about 1/3 had marginal vitamin B-6 deficiency [9].
Vitamin ‘B-9’, Folate: The vitamin once known as B-9 exists in foods as folate. Initially Food
folate was given for people with a pregnancy-related anemia in the form
of autolyzed yeast; later a synthetic USP isolate was developed [1].
Pteroylglutamic acid (folic acid), the common pharmacological (USP)
form of folate is not found significantly as such in the body [1].
“Folic acid is a synthetic folate form” [9]. Folic acid, such as in most supplements, is not found in Foods, folate is
[10]. Insufficient folate can result in fatigue, depression, confusion,
anemia, reduced immune function, loss of intestinal villi, and an
increase in infections [2]. Folate deficiency is the most important
determinant in high homocysteine levels [11], and supplemental folate
is effective in reducing homocysteine [11,12]. “The highest
concentrations of folate exist in yeast…and brocolli” [1]. Insufficient
folate can result in fatigue, depression, confusion, anemia, reduced
immune function, loss of intestinal villi, and an increase in
infections [2]. “(C)onsumption of more than 266 mcg of synthetic folic
acid (PGA) results in absorption of unreduced PGA, which may interfere
with folate metabolism for a period of years” [1]. A 2004 paper from
the British Medical Journal confirmed what many natural
health professional have known all along: since folic acid is unnatural
and the body cannot fully convert large amounts of it into usable
folate, this artificial substance can be absorbed and may have unknown
negative consequences in the human body [13], folate supplementation
obviously should be in Food folate forms and not folic acid!
Vitamin B-12 : Initially Foodvitamin
B-12 was given for people with pernicious anemia in the form of raw
liver, but due to cost considerations a synthetic USP isolate
(cyanocobalamin) was developed [6]. Cyanocobalamin, the common pharmacological (USP) form of vitamin B-12, is essentially cobalamins combined with cyanide!
[6]. The only two naturally active forms of vitamin B-12 in the human
body are methylcobalamin and deoxyadenosylcobalamin and those are in Food
[1]. Vitamin B-12 when ingested in its human-active form is non-toxic
[1], yet some researchers have concluded “The efficacy and safety of
the vitamin B-12 analogues created by nutrient-nutrient interaction in
vitamin-mineral supplements is unknown” [14]; interestingly some
synthetic vitamin B-12 analogues seem to be antagonistic to vitamin
B-12 activity in the body [15,16]! Insufficient vitamin B-12 results in
anemia, degeneration of peripheral nerves, and skin hypersensitivity
[1,2].
Vitamins B-6, B-12, and Folate are all important
nutrients for healthy blood; the absence of any of them can trigger
various forms of anemia (especially pernicious anemia) [1,14].Subclinical deficiencies in vitamin B-12, vitamin B-6, and folate may impair cognitive function [17].
Homocysteine responds to vitamin B-12 and folate [12].
Dr. Mason of Tufts University School of Medicine reports that a 20%
elevation of homocysteine significantly increases the risk of
cardiovascular disease [18]. Normal homocysteine level is about 12
umol/L, while cardiovascular risk increases about 14-16 umol/L [18]. In
addition, even if blood tests for vitamin B-12 or folate appear to be
normal, this may be because results are masked by an elevated level of
homocysteine. Homocysteine is highly implicated in vascular diseases
(such as cardiovascular and other vascular disorders), and can be
reduced with sufficient vitamin B-12 and Folate; with vitamin B-6
sometimes playing a supporting role [12].
Superoxide Dismutase
: “Superoxide dismutase (S.O.D.) is one of the most important enzymes
that function as cellular antioxidants...The absence of this enzyme is
lethal” [1]. “It protects intracellular components from oxidative
damage, converting the superoxide ion to hydrogen peroxide” [1]. S.O.D.
is a powerful free radical scavenger which has been clinically shown to
protect the brain, heart, liver, lungs, kidneys, skin, muscles, penis,
nerves, and spinal cord from ischemic injury [19]. High levels of
S.O.D. have been associated with reduced growth of Candida albicans [20]. 100% Food Vitamin B-6, B-12, and Folate naturally contains S.O.D.
Rice bran is also a Food complex source of silicon and B vitamins [2,21-24]. Since Vitamin B-6, B-12, & Folate contains only Foods, unlike other isolated supplements, it also naturally includes vitamin B-1 (thiamin), vitamin B-2 (riboflavin), vitamin
B-3 (niacinamide), vitamin B-5 (pantothenate), choline, inositol, and
other B vitamin factors which often work with vitamins B-6, B-12, and folate in the body. All these factors make 100% Food Vitamin B-6, B-12, & Folate the choice for doctors interested in truly natural health.
Many females simply take
Vitamin B-6, B-12, & Folate as a
Food supplement to help them feel better.
Supplement Facts
Serving Size 1 tablet
Servings per container 90
| Amount per serving |
|
|
|
|
|
RDI |
| Thiamin (B-1) |
|
(in 352 mg food) |
|
20 mcg |
|
* |
| Riboflavin (B-2) |
|
(in 352 mg food) |
|
20 mcg |
|
* |
| Niacinamide |
|
(in 352 mg food) |
|
105 mcg |
|
* |
| Vitamin B-6 |
|
(in 131 mg food) |
|
25 mg |
|
1250% |
| Folate |
|
(in 80 mg food) |
|
800 mcg |
|
200% |
| Vitamin B-12 |
|
(in 12 mg food) |
|
60 mcg |
|
1000% |
| Pantothenate |
|
(in 352 mg food) |
|
20 mcg |
|
* |
|
|
|
|
|
|
|
| Choline |
|
(in 196 mg food) |
|
.0 mg |
|
** |
| Inositol |
|
(in 196 mg food) |
|
0 mg |
|
** |
| Rice Bran |
|
Oryza sativa |
|
69 mg |
|
** |
* Contains less than 2% of RDI
** Recommended Daily Intake has not been established.
Other ingredients: Vegetable Lubricant, Silica, Guar Gum, Food Glaze.
|
Contains
naturally occurring carbohydrates, lipids, proteins (including all ten
essential amino acids), superoxide dismutase, and truly organic
bioflavonoids as found in enzymatically processed Saccharomyces cerevisiae, Rice bran Oryza sativa, Alfalfa sprouts Medicago sativa, and Mixed vegetable fiber Cellula vegetabalis all the nutrients shown above are contained in these foods. Unlike many so-called "natural" vitamin formulas, Food Vitamin B6, B12 & Folate is
a food vitamin formula (and not a synthetic isolate) contains no
synthetic USP nutrients, but only contains foods, food complexes, and
food concentrates.
Numerous
university studies have concluded that supplements containing food
nutrients are better than USP isolates. Food nutrients are better
because they contain important enzymes, peptides, and phytonutrients
CRITICAL to the UTILIZATION of vitamins and minerals which are not
present in isolated USP nutrients. Published research has concluded
that food vitamins are superior synthetic/USP vitamins.
Suggested
use: 1-2 tablets per day or as recommended by your health care
professional. Adjust usage according to nutritional lifestyle
requirements.
References
[1] Shils ME, Olson JA, Shike M. Modern Nutrition in Health and Disease, 9th ed. Williams & Wilkins, Balt., 1999
[2] Whitney EN, Hamilton EMN. Understanding Nutrition, 4th ed. West Publishing, NY, 1987
[3] Leklem JE. Vitamin B6. In Modern Nutrition in Health and Disease, 8th ed. Lea & Febiger, Phil.,1994:383-394
[4] Ensminger AH, Ensminger ME, Konlade JE, Robson JRK. Food & Nutrition Encyclopedia, 2nd ed. CRC Press, New York, 1993
[5] Shils ME, et al. Modern Nutrition in Health and Disease, 10th ed. Lipponcott Williams & Wilkins, Balt., 2006
[6] Mervyn L. The B Vitamins. Thorsons, Wellingborough (UK), 1981
[7] Vitamin-Mineral Manufacturing Guide Nutrient Empowerment, volume 1. Nutrition Resource, Lakeport (CA), 1986
[8] Glauser TA, Morita DA. Encephalopathic epilepsy after infancy. In
Pediatric Epilepsy, 2nd ed. Demos, New York, 2001:201-218
[9] Hendler SS, Rorvik D, eds. PDR for Nutritional Supplements. Medical Economics, Montvale (NJ), 2001
[10] Macrae R, Robson RK, Sadler MJ. Encyclopedia of Food Science and Nutrition. Academic Press, NY, 1993
[11] Verhoef P. Homocysteine metabolism and risk of myocardial
infarction: Relation with vitamin B6, B12, and Folate. Am J Epidemiol
1996;143(9):845-859
[12] Brattstrom L. Vitamins
as homocysteine-lowering agents: A mini review. Presentation at The
Experimental Biology 1995 AIN Colloquium, April 13, 1995, Atlanta
Georgia
[13] Lucock M. Is folic acid the ultimate functional food component for disease prevention? BMJ, 2004;328:211-214
[14] Shils ME, Olson JA, Shike M. Modern Nutrition in Health and Disease, 8th ed. Lea & Febiger, Phil., 1994
[15] Ishida A, Kanefusa H, Fujita H, Toraya T. Microbiological
activities in nucleotide loop-modified analogues of vitamin B12. Arch
Microbiol 1994;161(4):293-299
[16] Tandler B,
Krhenbul S, Brass EP. Unusual mitochondria in the hepatocytes of rats
treated with a vitamin B12 analogue. Anat Rec 1994;231(1):1-6
[17] Gonzalez-Gross M, Marcos A, Pietrzik K. Nutrition and cognitive impairment in the elderly. Br J Nutr 2001;86:313-321
[18] Brown S, et al. High serum homocysteine appear to be a risk factor. Family Practice News May 1, 1995:25
[19] Null G. Superoxide Dismutase. In The Clinician’s Handbook of Natural Healing. Kensington Books, New York, 1997:137-144
[20] Romandini P, Bonotto C, Bertoloni G, Beltramini M, Salvato B.
Superoxide dismutase, catalase and cell dimorphism in Candida albicans
cells exposed to methanol and different temperature. Comp Biochem
Physiol Pharm Toxicol Endocrinol,1994;108(1):53-57
[21] Thompson FE, et al. Sources of fiber and fat in the diets of U.S.
women ages 19 to 50: implications for nutritional education and policy.
Am J Pub Health 1992, 82(5):695-702
[22] Dietary fiber: importance of function as well as amount. Lancet 1992, 340:1133-1134
[23] Jensen B. The Chemistry of Man. Bernard Jensen, Escondido, 1983
[24] Nielsen FH. Ultratrace minerals. In Modern Nutrition in Health and
Disease, 9th ed. Williams and Wilkins, Balt.;1999:283-303
Some
of these studies (or citations) may not conform to peer review
standards, therefore, the results are not conclusive. Professionals
can, and often do, come to different conclusions when reviewing
scientific data. None of these statements have been reviewed by the
FDA. All products distributed by Doctors’ Research, Inc.
are nutritional and are not intended for the treatment or prevention of
any medical conditions .