There
is no doubt that we live in a high stress society. Not only do we
live and work in unnatural environments, our foods are vastly different
than they were 150 years ago. Until relatively recently, no human
ever consumed synthesized isolated USP vitamins. Should stress
vitamin formulas be primarily synthetic substances which can add stress to the body? We think not!
Vegetarian Adrenal is a 100% vegan Food
supplement intended to nutritionally support the adrenal glands and
help support biochemical imbalances associated with cortisol
production. The adrenal glands play a role in energy, stress,
mood, and even pain control. The adrenal glands have probably the
greatest store of vitamin C in the body. Vegetarian Adrenal is basically Food
intended for the adrenal glands (it is not advised if breastfeeding).
If additional endocrine support is indicated, consider adding Vegetarian Thyro or Vegetarian Tyrosine.
Acerola Cherry is one of the most vitamin C dense Foods
(the adrenal glands tend to store vitamin C in the body [1]) Not only
does it have free radical scavenging abilities, it also has been shown
to increase the antioxidant abilities of some other foods [2].
Ashwagandha Withania
somnifera is considered to be an herb to help deal with stress.
An animal study, “concluded that ashwagandha possesses adaptogenic,
cardiotropic, cardioprotective and anticoagulant properties” [3].
Carob Pod Ceratonia
siliqua is a natural Food source high in the amino acid serine (see
L-Serine below) [4]. In addition, research has concluded, “The
presence of substances with central benzodiazepine activity in carob
extracts seems of great importance in view of the possibility to use
carob extract as potential natural products with anxiolytic-sedative
effects” [5].
Kelp is Food that supplies trace minerals [6], and adrenal glands contain trace minerals.
L- Serine is an
non-essential amino acid, that along with some others help produce the
“enzyme that catalyzes the first step in the conversion of circulating
dehydroepiandrosterone (DHEA), pregnenolone or
17alpha-hydroxypregenolone to produce the appropriate, active steroid
hormone(s): estradiol, testosterone, progesterone, aldosterone or
cortisol respectively” [7]. L-serine is known to help restore
compromised adrenal function, as well as helping to reduce elevated
cortisol levels.
Potassium is found in
plants [8]. Potassium is the leading intracellular electrolyte and is
necessary for electrolyte balance, stimulating aldersterone for the
adrenal glands [8]. The late Dr. Bernard Jensen wrote the
following about potassium deficiencies, “The mind becomes chaotic,
unpredictable, highly imaginative and unorthodox. States of mind
alternate between joy and melancholy and even excitability…Potassium Must be Supplied in Food Form” [9] (bolding his).
Rice bran is a Food source of B vitamins [7], which are often used for stress, anxiety, and adrenal support.
Tomato powder contains lycopene in tomato powder. The power, which is how it is in Vegetarian Adrenal,
appears to be more bioavailable than that in fresh tomatoes, and tomato
powder has (by weight) 26-144 times more lycopene than fresh tomatoes
[7]. “Among the common dietary carotenoids lycopene has the highest
singlet oxygen quenching capacity in vitro. Other outstanding features
are its high concentration in… {the} adrenal gland” [10]. Studies
suggest it has a variety of protective effects [7].
Vitamin B-5 Pantothenate
is “the number one adrenal strengthener” [11]. Severe deficiency of
vitamin B-5 causes numbness in toes and painful burning in feet, and
can cause anemia, skin problems, and adrenal problems [12].
Because of cortisol’s anti-allergy properties this may be why many
advise pantothenate for allergies. “Synthetic D-pantothenate...is
available as a calcium or sodium salt” [12], and is sold in forms such
as sodium D-pantothenate or calcium D-pantothenate or sometime just
listed as pantothenic acid [13]. Other synthetic “multivitamin
preparations commonly contain its...alcohol derivative, panthenol”
[12]. “Dexopanthenol is a synthetic form which is not found
naturally” [13]. USP pantothenic acid is made by condensing
isobutyraldehyde with formaldehyde [14]. “Pantothenic acid
consists of pantoic acid in amide linkage to beta-alanine”, but vitamin
B-5 is not found that way in nature, pantothenate forms are [15].
The vegetarian foods which are highest in pantothenate are nutritional
yeast, brown rice, peanuts, and broccoli [12,13,15]. Nutritional
yeast and brown rice supply the vitamin B-5 in Vegetarian Adrenal, and
are two of the best natural sources of food pantothenate [12,13].
Vitamin B-6 : “An
understanding of the various forms [of vitamin B-6] and quantities of
these forms in foods is important in the evaluation of the
bioavailability and metabolism of vitamin B-6” [16]. One of the forms
that vitamin B-6 exists in is the form “5’0-(beta-D-glycopyransosyl)
pyridoxine. To date only plant foods have been found to contain
this interesting form of vitamin B-6” [16]. Yeast and rice bran
contain more natural food vitamin B-6 than other foods
[17]. Reports suggest that food vitamin B-6 is superior to
forms [18]. At least one synthetic vitamin B-6 analogue has been
found to inhibit natural vitamin B-6 action [19]. Pyridoxine HCL
(hydrochloride) which is found in most non-food supplements is made
with petroleum ester combined with HCL and processed with formaldehyde
[20]. “Disorders treated with (B-6)...include Down’s syndrome,
autism, hyperoxaluria, gestational diabetes, carpal tunnel syndrome,
depression, and diabetic neuropathy” [12]. Many problems
including anemias, premenstrual dysphoric disorder (PMDD), PMS,
cardiovascular complaints, confusion, depression, irritability, and
certain immune problems have responded to vitamin B-6 [21]. A
study of healthy elderly individuals found about 1/3 had marginal
vitamin B-6 deficiency [21].
Vitamin C in the human body, is
found in the greatest abundance in the adrenal glands, which
demonstrates that many aspects of adrenal physiology require vitamin
C. Foods generally contain two biologically active forms of vitamin C
[12,22,23], yet most synthetic vitamin C only contains isolated
ascorbic acid [24,25]. One M.D. writes, “If anything helps you battle
the effects of stress, it is vitamin C” [26]; vitamin C “can readily
donate electrons to quench a variety of reactive free radical and
oxidative species and is easily returned to its reduced state...The
vitamin efficiently scavenges hydroxyl, peroxyl, and superoxide
radicals, as well as reactive peroxide, singlet oxygen, and
hypochlorite species” and protects against lipid and low-density
lipoprotein (LDL) peroxidation” [12].

Many people simply take Vegetarian Adrenal as a Food supplement to help them feel better.
Nutrition from food, what a concept!
References
[1] Guyton AC, Hall JE. Textbook of Medical Physiology, 9th ed. WB Saunders, Phil., 1996
[2] Hwang J, Hodis HN, Sevanian A. Soy and alfalfa phytoestrogen
extracts become potent low-density lipoprotein antioxidants in the
presence of acerola cherry extract. J Agric Food Chem.
2001;49(1):308-314
[3] Dhuley JN. Adaptogenic and cardioprotective action of
ashwagandha in rats and frogs. J Ethnopharmacol. 2000 Apr;70(1):57-63
[4] USDA. Carob Powder. USDA National Nutrient Database for Standard Reference, Release 18 (2005)
[5] Avallone R, Cosenza F, Farina F, Baraldi C, Baraldi M. Extraction
and purification from Ceratonia siliqua of compounds acting on central
and peripheral benzodiazepine receptors. Fitoterapia. 2002;73(5):390-396
[6] Pederson M. Nutritional Herbology: A Reference Guide to Herbs, 3rd ed. Whitman Books, Warsaw (IN), 1998
[7] Sheldon S, Rorvik D, eds. PDR for Nutritional Supplements. Medical Economics, Montvale (NJ), 2001
[8] Whitney EN, Hamilton EMN. Understanding Nutrition, 4ed. West Publishing, New York, 1987
[9] Jensen B. The Chemistry of Man. Bernard Jensen Enterprises, Escondido (CA), 1983
[10] Gerster H. The potential role of lycopene for human health. J Am Coll Nutr. 1997;16(2):109-126
[11] Null G. The Complete Encyclopedia of Natural Health. Kensington Books, NY, 1998
[12] Shils ME, Olson JA, Shike M. Modern Nutrition in Health and
Disease, 9th ed. Williams & Wilkins, Balt., 1999
[13] Hendler S, Rorvik D, editors. PDR for Nutritional Supplements. Medical Economics, Montvale (NJ), 2001
[14] Vitamin-Mineral Manufacturing Guide Nutrient Empowerment, volume 1. Nutrition Resource, Lakeport (CA), 1986
[15] Plesofsky-Vig N. Pantothenic acid and Coenzyme A. In
Modern Nutrition in Health and Disease, 8th ed. Lea &
Febiger, Phil.,1994:395-401
[16] Leklem JE. Vitamin B6. In Modern Nutrition in Health
and Disease, 8th ed. Lea & Febiger, Phil.,1994:383-394
[17] Ensminger AH, Ensminger ME, Konlade JE, Robson JRK. Food
& Nutrition Encyclopedia, 2nd ed. CRC Press, New York, 1993
[18] Thiel R. Natural vitamins may be superior to synthetic ones. Medical Hypotheses, 2000; 55(6):461-469
[19] Mervyn L. The B Vitamins. Thorsons, Wellingborough (UK), 1981
[20] Vitamin-Mineral Manufacturing Guide Nutrient Empowerment, volume 1. Nutrition Resource, Lakeport (CA), 1986
[21] Hendler SS, Rorvik D, eds. PDR for Nutritional Supplements. Medical Economics, Montvale (NJ), 2001
[22] Levine, M, et al. Vitamin C. In Present Knowledge in
Nutrition, 7th ed. ILSI Press, Washington, 1996:146-159
[23] Vanderslice JT, Higgs DJ. Vitamin C content of foods: sample
variability. Am J Clin Nutr, 1991;54(Supp 6):1323S-1327S
[24] The United States Pharmacopeial Convention. USAN and USP
Dictionary of Drug Names. Mack Printing, Easton (PA),1986
[25] Mangels AR, et al. The bioavailability to humans of ascorbic
acid from oranges, orange juice and cooked broccoli is similar to that
of synthetic ascorbic acid. J Nutr, 1993;123(6):1054-1061
[26] Understanding Vitamins and Minerals. Rodale Press, Emmaus (PA), 1984
Some of
these studies (or citations) may not conform to peer review standards,
therefore, the results are not conclusive. Professionals can, and often
do, come to different conclusions when reviewing scientific data. None
of these statements have been reviewed by the FDA. All
products distributed by Doctors’ Research, Inc. are nutritional and are
not intended for the treatment or prevention of any medical
condition.